SIMULTANEOUS ANALYSES OF CLUTCH COUPLING AND ACTIN POLYMERIZATION IN DENDRITIC SPINES OF RODENT HIPPOCAMPAL NEURONS DURING CHEMICAL LTP

Simultaneous analyses of clutch coupling and actin polymerization in dendritic spines of rodent hippocampal neurons during chemical LTP

Summary: Dendritic spine enlargement by synaptic activation is thought to increase synaptic efficacy underlying learning and memory.This process requires forces generated by actin polymerization and actin-adhesion coupling (clutch coupling).Here, we describe a protocol to monitor actin filament retrograde flow and actin polymerization within spines

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Microemulgel: a novel approach for topical drug delivery

Topical drug delivery is mostly preferred for dermatological action.Topical dosage form such as cream, ointments, gels etc.has certain drawbacks like stability problems, stickiness, poor absorption Fridge Crisper Lid Frame as well as permeability.It has limitations in terms of drug solubility, residence time, lipophilicity and permeability.To overc

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Evaluation of coupled finite element/meshfree method for a robust full-scale crashworthiness simulation of railway vehicles

The crashworthiness of a railway vehicle relates Shower Caps to its passive safety performance.Due to mesh distortion and difficulty in controlling the hourglass energy, conventional finite element methods face great challenges in crashworthiness simulation of large-scale complex railway vehicle models.Meshfree methods such as element-free Galerkin

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